SOS regulation of qnrB expression.
نویسندگان
چکیده
In the sequence upstream from qnrB (but not qnrA or qnrS) is a LexA binding site. qnrB was shown to be under SOS control by demonstrating that quinolone susceptibility decreased with increasing temperature in a strain with a recA441(Ts) allele, whereas qnrB expression increased in response to ciprofloxacin or mitomycin C in strains with an intact lexA gene.
منابع مشابه
The SOS response promotes qnrB quinolone-resistance determinant expression.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 53 2 شماره
صفحات -
تاریخ انتشار 2009